César Nombela Selected Research

Systemic candidiasis

1/2015	Proteomics unravels extracellular vesicles as carriers of classical cytoplasmic proteins in Candida albicans.
1/2012	Estradiol impairs the Th17 immune response against Candida albicans.
4/2008	Serological proteome analysis to identify systemic candidiasis patients in the intensive care unit: Analytical, diagnostic and prognostic validation of anti-Candida enolase antibodies on quantitative clinical platforms.
10/2007	Reliability of antibodies to Candida methionine synthase for diagnosis, prognosis and risk stratification in systemic candidiasis: A generic strategy for the prototype development phase of proteomic markers.
1/2006	Decoding serological response to Candida cell wall immunome into novel diagnostic, prognostic, and therapeutic candidates for systemic candidiasis by proteomic and bioinformatic analyses.
10/2004	Proteomics-based identification of novel Candida albicans antigens for diagnosis of systemic candidiasis in patients with underlying hematological malignancies.
10/2004	Low virulent strains of Candida albicans: unravelling the antigens for a future vaccine.
4/2004	Contribution of the antibodies response induced by a low virulent Candida albicans strain in protection against systemic candidiasis.

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César Nombela Research Topics

Disease

8	Systemic candidiasis 01/2015 - 04/2004
6	Infections 01/2018 - 01/2009
4	Candidiasis (Moniliasis) 01/2012 - 10/2004
3	Invasive Candidiasis 01/2015 - 01/2011
2	Candidemia 03/2016 - 02/2016
2	Porcine Reproductive and Respiratory Syndrome (PRRS) 10/2013 - 05/2009
2	Inflammation (Inflammations) 08/2012 - 06/2009
1	Hypersensitivity (Allergy) 01/2019
1	Critical Illness (Critically Ill) 01/2018
1	Communicable Diseases (Infectious Diseases) 03/2016
1	Wounds and Injuries (Trauma) 01/2008
1	Starvation 03/2007
1	Hematologic Neoplasms (Hematological Malignancy) 10/2004
1	Mycoses (Diseases, Fungus) 10/2004

Drug/Important Bio-Agent (IBA)

11	Proteins (Proteins, Gene)FDA Link 01/2018 - 10/2004
8	AntibodiesIBA 01/2018 - 04/2004
4	Biomarkers (Surrogate Marker)IBA 01/2018 - 10/2004
4	VaccinesIBA 03/2016 - 10/2004
4	Phosphopyruvate Hydratase (Enolase)IBA 02/2016 - 10/2004
3	AntigensIBA 01/2018 - 10/2004
3	ProteomeIBA 02/2016 - 04/2008
2	MannansIBA 01/2018 - 01/2008
2	Interleukin-23 (Interleukin 23)IBA 01/2018 - 01/2012
2	Peptides (Polypeptides)IBA 03/2016 - 10/2004
2	Phosphoglycerate Kinase (Kinase, Phosphoglycerate)IBA 02/2016 - 10/2004
2	LipidsIBA 01/2008 - 03/2007
1	Messenger RNA (mRNA)IBA 01/2019
1	ProcalcitoninIBA 01/2018
1	Interleukin-17 (Interleukin 17)IBA 01/2018
1	arabitol (D-arabinitol)IBA 01/2018
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2018
1	polyglucosanIBA 01/2018
1	Peptide Nucleic AcidsIBA 01/2018
1	Serum Amyloid A Protein (Serum Amyloid A)IBA 01/2018
1	Immunoglobulin G (IgG)IBA 02/2016
1	Blood Proteins (Serum Proteins)IBA 01/2015
1	PhosphoproteinsIBA 10/2013
1	Pattern Recognition ReceptorsIBA 10/2013
1	Estradiol (Delestrogen)FDA LinkGeneric 01/2012
1	Oral ContraceptivesIBA 01/2012
1	GTP Phosphohydrolases (GTPases)IBA 06/2009
1	Pathogen-Associated Molecular Pattern MoleculesIBA 05/2009
1	bis(monoacylglyceryl)phosphateIBA 04/2009
1	Membrane Proteins (Integral Membrane Proteins)IBA 07/2008
1	ChitinIBA 01/2008
1	GlucansIBA 01/2008
1	Polysaccharides (Glycans)IBA 01/2008
1	5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase (Methyltetrahydrofolate Homocysteine Methyltransferase)IBA 10/2007
1	glyoxylic acid (glyoxylate)IBA 03/2007
1	Fatty Acids (Saturated Fatty Acids)IBA 03/2007
1	CarbonIBA 03/2007
1	Alcohol Dehydrogenase (Alcohol Dehydrogenase (NAD+))IBA 10/2004
1	Pharmaceutical PreparationsIBA 10/2004
1	Phosphotransferases (Kinase)IBA 10/2004
1	MitogensIBA 10/2004

Therapy/Procedure

2	Therapeutics 01/2018 - 04/2008
2	Lasers (Laser) 01/2018 - 10/2004
1	Hormone Replacement Therapy (Therapy, Hormone Replacement) 01/2012
1	Immunotherapy 01/2009